Abstract Due to the overexpression or amplification of human epidermal growth factor receptor 2 (HER2) with poor prognosis in a myriad of human tumors, recent studies have focused on HER2-targeted therapies.Deregulation in HER2 signaling pathways is accompanied by sustained tumor cells growth concomitant with their migration and also tumor angiogen
The bacterial flagellar motor is a highly efficient rotary machine used by many bacteria to propel themselves.It has recently been shown that Creatine at low speeds its rotation proceeds in steps.Here we propose a simple physical model, based on the storage of energy in protein springs, that accounts for this stepping behavior as a random walk in a
Abstract Background Although it is well known in the literature that high triglyceride serum (TG) levels can jeopardize the metabolic control, little is known about the influence of low TG on type 1 diabetes patients (T1D).The aim of this study is to investigate the distribution of TG serum levels in individuals with T1D and its relationship with S
During the reconstruction, or upon expiration of the service life, as well as after external impact, Mucuna Pruriens reinforced concrete structures require examination and verification calculations.Existing diagrams of concrete deformation are focused on designing new structures and are not adapted to the concretes of the reconstructed structures.U
Background and Aim: Left ventricular myocardial remodeling could play an important role in the progression of chronic heart failure (CHF) syndrome in dogs with mitral valve endocardiosis.The aim of this study was to evaluate the left ventricular myocardial remodeling in dogs with mitral valve endocardiosis and to study the dependence of the inciden